BiobankCell BiologyBio-Analysis

Adipocytes

Adipocytes compose the adipose tissues, storing energy in the form of fat. Two types of adipose tissues are identified, known as white adipose tissue and brown adipose tissue.  White fat cells are characterized by containing a large lipid droplet surrounded by cytoplasm. The fat is semi-liquid and composed of triglycerides and cholesterol. White fat cells secrete resistin, adiponectin and leptin. The lineage of adipocytes remains unclear, though it has been reported that pre-adipocytes are undifferentiated fibroblasts that can differentiate into adipocytes.

Human Pre-adipocytes (HPAd) are fibroblast-like precursor cells cryopreserved at the end of primary culture and can be propagated two passages prior to differentiating into Human Adipocytes (HAd). HPAd/HAd are useful in vitro cellular models for investigating the causes and treatment of obesity, type II diabetes and cardiovascular diseases. Previously, most research in adipocyte biology was conducted in mouse 3T3-L1 cell lines. To facilitate the study of human adipocyte biology, Human Adipocytes (Had) can be differentiated from Human Preadipocytes (HPAd) using   Adipocyte Differentiation Medium. Mature HAd are obtained ~15 days after induction of differentiation and remain healthy and responsive for at least 2 weeks thereafter.

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Products

Ref Products Associated Products Price
CM-1041-111 Cryoconserved Human Preadipocytes (HPAd) (>500,000 cells), subcutaneous, adult Culture Media CM-3041-041, CM-3041-051, CM-3041-061 247.00 €
CM-1041-211 Cryoconserved Functionally Characterised Preadipocytes (HPAd) (>500,000 cells), subcutaneous, adult Culture Media CM-3041-041, CM-3041-051, CM-3041-061 412.50 €
CM-1041-161 Proliferating Human Preadipocytes (HPAd) (2* T75 flasks), subcutaneous, adult Culture Media CM-3041-041, CM-3041-051, CM-3041-061 547.50 €
CM-1041-261 Proliferating Functionally Characterised Human Preadipocytes (HPAd) (2* T75 flasks), subcutaneous, adult Culture Media CM-3041-041, CM-3041-051, CM-3041-061 747.50 €
CM-1045-161 Differentiated Human Preadipocytes (HPAd) (2* T75 flasks), subcutaneous, adult Culture Media CM-3041-041, CM-3041-051, CM-3041-061 702.00 €