CD14+ Monocytes

Since 2007, CellMade™ has specialized in Purified CD14+ Monocytes, providing high-purity (>95%) assay reagents engineered for the most sensitive readouts in pyrogenicity and cytokine release testing. By eliminating the "chemical noise" of non-responding lymphocytes found in standard PBMCs, these cells deliver a superior signal-to-noise ratio and enhanced detection limits for the Monocyte Activation Test (MAT), in full compliance with Ph. Eur. 2.6.30. Available in single-donor or the regulatory-preferred 8-donor pooled formats, every lot is pre-qualified for reliable secretion of IL-6, IL-1β, and TNF-α with guaranteed >90% post-thaw viability. This functionally characterized model ensures absolute experimental consistency for drug safety assessments and biologics, supported by a comprehensive technical onboarding process that includes feasibility, validation, and on-site method transfer.